Description
MOTS-C is a 16-amino-acid peptide encoded not by the cell nucleus but by mitochondrial DNA, and it has become a leading subject in metabolic research. Limitless Life Nootropics supplies it in 5mg and 10mg vials, made in the USA.
What Is MOTS-C?
The peptide was discovered in 2015 by researchers at the University of Southern California, who found a short open reading frame inside the mitochondrial 12S rRNA gene. Its name stands for Mitochondrial Open reading frame of the Twelve S rRNA type-c, and its sequence is Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg.
In preclinical studies, it has been shown to activate AMPK, a central energy sensor in cells, and to improve insulin sensitivity in mice fed a high-fat diet. Under metabolic stress, it can move into the nucleus and influence gene expression, an unusual form of communication from the mitochondria to the nucleus.
Premium lyophilized and Non-Lyophilized grades are available in 5mg and 10mg sizes.
Areas of Scientific Investigation
Laboratory studies have explored this peptide across several areas of investigation:
- AMPK activation and glucose metabolism
- Insulin resistance in diet-induced obesity models
- Exercise capacity and muscle metabolism in aging mice
- Mitochondrial–nuclear signaling
- Combined studies with Humanin
Researchers can review peer-reviewed studies on this mitochondrial peptide through the National Library of Medicine (PubMed) database.
MOTS-C Specifications
| Product | MOTS-C |
|---|---|
| Compound type | Mitochondrial-derived peptide (16 amino acids) |
| Available sizes | 10mg, 5mg |
| Format | Lyophilized (freeze-dried) powder in a sealed glass vial |
| Purity | ≥99% (HPLC verified) |
| Origin | Manufactured in the USA |
| Testing | Independent third-party lab |
| Intended use | Laboratory research only |
The Limitless Life Nootropics Standard
Independent researchers, university groups and private laboratories rely on Limitless Life Nootropics for consistent quality and responsive service. Every listing includes accurate format and size information, our compounds are stored under controlled conditions until they ship, and we stand behind every order. If something is not right, our U.S.-based support team will make it right.
Quality and Third-Party Testing
Limitless Life Nootropics sources this peptide from U.S. facilities that follow Good Manufacturing Practice principles. Each lot is sent to an independent laboratory for purity (HPLC) and identity (mass spectrometry) testing before release, giving your team consistent, traceable material from one experiment to the next.
Storage and Handling
Unopened lyophilized this peptide remains most stable when frozen at -20°C and protected from light. After reconstitution with a suitable diluent, refrigerate at 2–8°C and avoid repeated freeze-thaw cycles.
Need supplies? Pair your order with our reconstitution solution and sterile 10 mL vials for convenient preparation.
Ordering and Shipping
Buying from Limitless Life Nootropics is simple: add the size you need to your cart, complete encrypted checkout, and receive tracking details as soon as your package leaves our U.S. facility. Orders typically ship within one to two business days in plain, protective packaging, and our team is available for lot documentation or bulk research requests.
Related Research Products
Teams working with this peptide often explore MOTS-C/Humanin (Blend), 5-Amino-1MQ Capsules and 5-Amino-1MQ Powder. Browse the full Metabolic Research and Mitochondrial Research collections, or view every compound in our research peptide catalog at Limitless Life Nootropics.
Frequently Asked Questions
Where does this peptide come from?
It is encoded in the 12S rRNA region of mitochondrial DNA rather than in nuclear DNA.
What sizes are available?
This peptide is offered in 5mg and 10mg vials.
Is MOTS-C for human use?
No. It is sold strictly for laboratory research. It is not intended for human or animal consumption, diagnosis or treatment.
Where can I buy MOTS-C online?
You can order it directly from Limitless Life Nootropics, a U.S. supplier of third-party tested research peptides with fast, discreet shipping.
Research Use Only
All products sold by Limitless Life Nootropics are intended strictly for in-vitro laboratory research and scientific study. This product is not a drug, food, supplement or cosmetic, has not been evaluated by the FDA, and is not for human or veterinary use. Purchase is limited to qualified researchers aged 21 and over.
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